Dr. Michael R. Ladisch
Distinguished Professor of Agricultural and Biological Enineering
BS, Drexel University
MS, PhD, Purdue University
Affiliations
Member, National Academy of Engineering
Sigma Xi
Tau Beta Pi
Phi Eta Sigma
Phi Lambda Upsilon
American Institute of Biological Engineers (AIMBE)
American Institute of Chemical Engineers (AIChE)
American Chemical Society (ACS)
American Society of Agricultural and Biological Engineers (ASABE)
American Association for the Advancement of Science (AAAS)
Institute for Biological Engineering (IBE)
Professor in the Weldon School of Biomedical Engineering
Courtesy Appointment Professor in Food Science
Research
Dr. Ladisch’s research addresses fundamental topics in bioprocess engineering as it applies to bioproducts, biorecovery, and bionanotechnology. The work that he carries out with teams of researchers consisting of colleagues, graduate students, and staff is multi-disciplinary and multi-institutional, and addresses properties of proteins and living organisms at surfaces, rapid prototyping of microfluidic biosensors, bioseparations, and transformation of renewable resources into bioproducts. His research has resulted in new industrial bioenergy processes, and systematic approaches and correlations for scaling-up laboratory chromatographic purification techniques to process-scale manufacturing systems. He is currently investigating the scale-down of bioseparations and the rapid prototyping of microfluidic biochips for the rapid detection of pathogenic microorganisms.
Selected Publications
Ladisch, M. R. and B. Dale, “Distillers’ Grains: On the Pathway to Cellulose Conversion”, Bioresource Technology, (in press).
Vermerris, W., A. Saballos, G. Ejeta, N. S. Mosier, M. R. Ladisch, and N. C. Carpita, “Molecular Breeding to Enhance Ethanol Production from Corn and Sorghum Stover,” Crop Science, 47(S3), S142-S153 (2007).
Zeng, M., Mosier, N.S., Huang, C-P, Sherman, D. M., and Ladisch, M. R., “Microscopic Examination of Changes of Plant Cell Structure in Corn Stover Due to Hot Water Pretreatment and Enzymatic Hydrolysis,” Biotechnology and Bioengineering, 97(2), 265-278 (2007).
Huang, T. T., D. G. Taylor, K.-S. Lim, M. Sedlak, R. Bashir, N. S. Mosier, and M. R. Ladisch, “Surface-Directed Boundary Flow in Microfluidic Channels, Langmuir, 22(14), 6429-6437 (2006).
Yang, L., P. P. Banada, M. R. Chatni, K.-S. Lim, A. K. Bhunia, M. Ladisch and R. Bashir, “A Multifunctional Microfluidic System for Dielectrophoretic Concentration Coupled with Immuno-capture of Low Numbers of Listeria monocytogenes, Lab Chip, 6, 896-905 (2006).
Huang, T. T., N. S. Mosier, and M. R. Ladisch, “Review: Surface Engineering of Microchannel Walls for Protein Separation and Directed Microfluidic Flow, “Journal of Separation Science, 29 (in press, 2006).
Gupta, A., P. R. Nair, D. Akin, M. R. Ladisch, S. Broyles, M. A. Alam, and R. Bashir, “Anomalous Resonance in a Nanomechanical BioSensor,” PNAS (2006).
Chen, W.-T., T. Geng, A. K. Bhunia, and M. R. Ladisch, “Membrane for Selective Capture of the Microbial Pathogen Listeria monocytogenes, AIChE J., 51(12), 3305-3308 (2005).
Kim, Y., R. Hendrickson, N. Mosier, and M. R. Ladisch, “Plug Flow Reactor for Continuous Hydrolysis of Glucans and Xylans from Pretreated Corn Fiber,” Energy and Fuels (an American Chemical Society Journal), 19(5), 2189-2200 (2005).
Wyman, C. E., B. E. Dale, R. T. Elander, M. Holtzapple, M. R. Ladisch, and Y. Y. Lee, “Coordinated Developnent of Leading Biomass Pretreatment Technologies,” Bioresource Technology, 96, 1959-1966 (2005).
Awards and Honors
Inaugural recipient of Paul Dana Biotech Award (2006)
Agricultural Team Award (Biosensor Detection Team (2006)
Outstanding Chemical Engineer Award (2006)
Marvin J. Johnson Award in Biochemical Technology (for exceptional research, leadership in bioseparations, biocatalysis, and biomass conversion), American Chemical Society Division of Biochemical Technology (2002)
Food, Pharmaceutical and Bioengineering Division Research Award, (for AIChE) American Institute of Chemical Engineers (2001)
Sigma Xi Faculty Research Award, Purdue University (2000)
Member of the National Academy of Engineering (1999)
North American Region Business Award (for industry/university catalysis team), Rohm and Haas Co., (1996)
Fellow of the American Institute of Medical and Biological Engineering (1994)
Best Teacher Award, Agricultural Engineering Department (1991)
James M. Van Lanen Distinguished Service Award (for service to fermentation science and fermentation industry), Division of Biochemical Technology, American Chemical Society (1990)
Science Support Grant in Bioseparations and Engineering of Multi-component Separations, ALCOA Foundation (1986)
Purdue University Agricultural Research Award (1986)
U.S. Presidential Young Investigator Award (1984)
W. H. Peterson Award of the Microbial and Biochemical Technology Division of the American Chemical Society for Best Graduate Student Paper in the Division’s Program (1977)
Margaret Hildebrand Award, Chemical Engineering Department, Drexel University (1973)
Contact Dr. Ladisch
e-mail: ladisch@purdue.edu
Address:
Laboratory of Renewable Resources Engineering
500 Central Drive
West Lafayette, Indiana 47907-2022 Phone: (765) 494-7023