Dr. Joseph Irudayaraj

Associate Professor

B.S., College of Agric. & Bio. Engineering, India, Agric and Bio. Engin.
M.S., University of Hawaii, Honolulu, HI, Information & Computer Sciences
M.S., University of Hawaii, Honolulu, HI, Biosystems Engineering
Ph.D., Purdue University, Bioprocess Engineering

Research

Our focus is to develop biosensors, nanotools, and single molecule methods relevant to detection, diagnosis, and prognosis of diseases. Single molecule methods as tools for understanding, asking, and answering fundamental biological questions are at the heart of our research and teaching efforts. Biosensing strategies with multiplexing capabilities to monitor biomolecular events at single molecule and single particle resolution both at the cellular and molecular level are researched. Applications are in cancer detection and diagnostics, cell communications and signaling.

Teaching

Undergraduate

ABE 495X: Fundamentals of Nanobiotechnology

Graduate

ABE 591T: Intro to Biophysics

Selected Publications

Yu, C. Naksharti, H., and Irudayaraj, J. 2007. Identity profiling of cell surface markers by multiplex gold nanorod probes. Nano Letters, 7(8):2300-2306.

Yu, C. and Irudayaraj, J. 2007. Surface modification of CTAB capped gold nanorods. Langmuir, 23:9114-9119.

Yu, C. and Irudayaraj, J. 2007. Sensitivity and Selectivity limits of multiplex nanoSPR biosensor assays. Biophysical Journal. 93(9):1-9 (Nov 2007 Issue).

Kouassi, G., Wang, P., Sreevatsan, S. Irudayaraj, J. 2007. Detection of prion protein on streptavidin-aptamer mediated magnetic and gold-coated magnetic nanoparticles. Biotech Progress. (23) 1239-1244.

Sun, L., Yu, C., and Irudayaraj, J. 2007. Surface enhanced raman scattering based nonfluorescent probes for multiplex DNA detection. Analytical Chemistry, 79(11):3981-3988.

Shamsaie, A. and Irudayaraj, J. 2007. Intracellularly Grown Gold Nanoparticles (IGAuN) as Potential SERS Probes. Journal of Biomedical Optics. 12(2):020502-1-3.

Yu, C. and Irudayaraj, J. 2007. A multiplex biosensor using gold nanorods. Analytical Chemistry. 79(2): 572-579. [2nd most accessed paper in Analytical Chemistry in April-June 2007]

Yu, C., Gestl, E., Eckert, K., Allara, D., Irudayaraj, J. 2006. Confocal Raman based differentiation and biomarker identification in human breast epithelial cells. Cancer Detection and Prevention. 30(6):515-522.

Yu, C. and Irudayaraj, J. 2006. Detection and identification of pathogenic microorganisms in mixed cultures by FTIR spectroscopy. Trans of ASABE, 49(5):1623-1632.

Kouassi, G. and Irudayaraj, J. 2006. A nanoparticle based immobilization assay for prion protein kinetics study. Journal of Nanobiotechnology. 4(8): 1-10.

Awards and Honors

• Purdue University, Office of the VP, recognition for team/center grants
• Best Paper award, ASABE (2005)
• USDA CSREES: Group honor award and Certificate for NE 179 Multistate Research group, 2003
• Listed in Who’s Who: 18th Editon, 2001. Marquis Who’s Who
• 1999 – 2000 Young Engineer of the Year Award for Northeastern region [Agric.& Biol. Engin – ASAE)
• Innovation in Teaching Award (1997)
• Teacher of the Year Award (1997)
• 1987-1991 David Ross Research Fellowship (Purdue University)
• Merit Scholarships : 1979-1983 (Undergrad National Merit Scholarship, India)

Contact Dr. Irudayaraj
e-mail: josephi@purdue.edu

Address:
Department of Agricultural & Biological Engineering
1146 ABE Building
Purdue University
West Lafayette, IN 47907-1146 Phone: (765) 494-0388
Fax: (765) 496-1115