Lipid Chemistry & Molecular Biology Laboratory

The research conducted in our laboratories is directed at nutrition, biology and health to advance the understanding of food and life sciences. Bone and musculoskeletal biology: The major aim of this research is to determine the amounts and balance of dietary fatty acids for optimal human nutrition and health, and characterize their roles in bone biology and tissue atrophy in disuse. The first goal is to understand the interactions of fatty acids, prostanoids, and growth factors on bone metabolism. The research is directed at characterizing how specific fatty acids and phytochemicals impact bone modeling and remodeling. These experiments investigate actions in bone cell cultures and various animal models. Studies that examine fatty acids and gene modulation of osteoblast function/differentiation and expression of gene products associated with bone formation are of primary interest. The second goal is to determine the interactions of nutrients and flavonoids on bone remodeling during estrogen deficiency. Functional foods: The research aim is to determine the efficacy, delivery, and safety of phytochemicals and nutraceuticals in functional foods. Research on the chemistry and bioavailability of health protectants in food systems is conducted to evaluate delivery systems for functional food ingredients and determine applications for these compounds.

In teaching and learning our multimedia team is engaged in developmental efforts focused on science visualization to facilitate learning using CD-ROM and Internet educational programs for K-16. Examples include The Pizza Explorer CD-ROM and the Phytochemical Learning Resource.

Rooms 3248, 3248A, and 3258 - Lipid Chemistry and Molecular Biology Laboratory
Room 3283 - Cell Culture Laboratory
Room 3236 - X-Ray Bone Densitometry Laboratory

Modulatory effect of omega-3 polyunsaturated fatty acids on osteoblast function and bone metabolism

» Dr. Bruce Watkins (3/25/03)

Conjugated Linoleic Acids Alter the Fatty Acid Composition and Physical Properties of Egg Yolk and Albumen

Ectopic expression of IGF-I and Shh by skeletal muscle inhibits disuse-mediated skeletal muscle atrophy and bone osteopenia in vivo

Impact of Dietary n-3 FA Deficiency on Rat Bone Tissue FA Composition